Bolivia

Santa Cruz de la Sierra

The vibrant heart of tropical Bolivia

Bolivia

Why travel to Santa Cruz de la Sierra

In Bolivia's tropical lowlands, where the Andes tumble into the Amazon, Santa Cruz opens doors to landscapes found nowhere else on Earth. This is the gateway to Kaa-Iya, South America's largest protected dry forest, where jaguars prowl in densities rivaling the Pantanal. It's the starting point for the Jesuit Missions of Chiquitos, where 5,000 baroque music sheets were rediscovered in churches that still hold mass today. From Amboró's three-ecosystem collision to the mysterious carved rock of Samaipata, this region rewards those who venture beyond the expected.

Tours

Tours that visit Santa Cruz de la Sierra

2 tours · from $435 per person

Featured expedition 11 days

Bolivia's Wild East: Jaguars, Cloud Forest and Lost Missions

Journey through Amboro Park, Gran Chaco, and Chiquitania's Jesuit mission sites Explore this journey From $4,200

Build a trip around Santa Cruz de la Sierra

Santa Cruz serves as Bolivia's international gateway, with Viru Viru Airport handling flights from Miami, Madrid, and major South American cities.

  1. Tell us dates, group, budget and what matters most
  2. We draft a day-by-day itinerary with a price
  3. Refine it together, then book
Takes two minutes. No deposit until the plan is right.

1

The Three-Ecosystem Convergence

Nowhere else on Earth do three major ecosystems collide quite like they do around Santa Cruz. To the west, Amboró National Park marks where the Andes descend into lowland jungle; to the east, the Gran Chaco's dry forests stretch toward Paraguay; and threading between them, the Amazon basin's influence brings moisture and life. This convergence creates biological diversity that staggers even seasoned naturalists: Amboró alone harbors 912 bird species, more than the United States and Canada combined, within 4,425 square kilometers.

The region's centerpiece for wildlife is Kaa-Iya del Gran Chaco National Park. At 3.4 million hectares, it's Bolivia's largest protected area and the world's largest remaining tract of intact dry forest. Founded in 1995 through the initiative of the indigenous Guaraní-Isoceño people, Kaa-Iya protects over 1,000 jaguars, one of the densest populations anywhere. Here, pumas, tapirs, giant anteaters, and the rare Chacoan peccary, once thought extinct, share habitat with 350 bird species and the endangered maned wolf.

2

Living Heritage of the Missions

3

Where Empires Met at Samaipata

Things to do

Things to do around Santa Cruz de la Sierra

Plan your visit

Getting to Santa Cruz de la Sierra

Fly to Viru Viru International

From $600-1,200 USD round-trip

10-12 hours from US/Europe

Viru Viru International Airport (VVI), located 17 kilometers north of Santa Cruz, is Bolivia's main international gateway. Direct flights operate from Miami (Boliviana de Aviación), Madrid (Air Europa, BoA), and connections via Lima, São Paulo, and Buenos Aires serve most international origins.

Our tip

Book international flights 2-3 months ahead for best fares.

Overland to the Missions Circuit

From $80-150 USD per day (vehicle)

3-6 hours to first missions

The Jesuit Missions circuit begins 225 kilometers northeast of Santa Cruz at San Javier, reachable in about 3.5 hours on paved roads. The full six-mission loop covers approximately 500 kilometers over 2-4 days, with the eastern missions requiring unpaved road travel during dry season.

Our tip

Plan at least 3 days for a proper missions circuit.

Expedition to Kaa-Iya

From $200-350 USD per day (tour)

4-5 hours to park entrance

Kaa-Iya National Park lies 260 kilometers east of Santa Cruz via San José de Chiquitos. Access requires permits arranged through authorized operators, 4x4 vehicles, and experienced guides.

Our tip

Book Kaa-Iya expeditions at least 2 weeks ahead, since permits and ranger coordination take time.

Nearby

More places in Bolivia

  • Samaipata

    The ancient rock, the timeless valley. See the place
  • Amboro National Park

    Where the Andes meet the Amazon See the place
  • Kaa-Iya National Park

    Bolivia's Wildest Dry Forest and Jaguar Stronghold See the place
  • Sucre

    Bolivia’s Timeless White City See the place
  • Potosí

    Where History is Minted in Silver See the place
  • North Yungas Road

    The ultimate test between your brakes and your bravery See the place

From the journal

Stories from Santa Cruz de la Sierra

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